OverProt: secondary structure consensus for protein families-Reference-Cited by-同舟云学术

OverProt: secondary structure consensus for protein families

Published:2022-06-08 Issue:14 Volume:38 Page:3648-3650
ISSN:1367-4803
Container-title:Bioinformatics
language:en
Short-container-title:

Author:

Midlik Adam¹²^ORCID,Hutařová Vařeková Ivana²³⁴,Hutař Jan²,Chareshneu Aliaksei¹²,Berka Karel⁴^ORCID,Svobodová Radka¹²^ORCID

Affiliation:

1. CEITEC—Central European Institute of Technology, Masaryk University , 625 00 Brno, Czech Republic

2. National Centre for Biomolecular Research, Faculty of Science, Masaryk University , 625 00 Brno, Czech Republic

3. Department of Computer Systems and Communications, Faculty of Informatics, Masaryk University , 602 00 Brno, Czech Republic

4. Department of Physical Chemistry, Faculty of Science, Palacký University , 771 46 Olomouc, Czech Republic

Abstract

Abstract Summary Every protein family has a set of characteristic secondary structures. However, due to individual variations, a single structure is not enough to represent the whole family. OverProt can create a secondary structure consensus, showing the general fold of the family as well as its variation. Our server provides precomputed results for all CATH superfamilies and user-defined computations, visualized by an interactive viewer, which shows the secondary structure element type, length, frequency of occurrence, spatial variability and β-connectivity. Availability and implementation OverProt Server is freely available at https://overprot.ncbr.muni.cz. Supplementary information Supplementary data are available at Bioinformatics online.

Funder

Ministry of Education, Youth and Sports

Czech Republic

e-INFRA CZ

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

Link

https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btac384/44113894/btac384.pdf

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