1. Department of Statistics, TU Dortmund University, Dortmund 44221, Germany
2. Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany
3. Department of Toxikologie/Systemtoxikologie, Leibniz Research Centre for Working Environment and Human Factors (IfADo), TU Dortmund University, Dortmund 44139, Germany