Molecular causes of transcriptional response: a Bayesian prior knowledge approach

Author:

Zarringhalam Kourosh11,Enayetallah Ahmed1,Gutteridge Alex1,Sidders Ben1,Ziemek Daniel1

Affiliation:

1. Computational Sciences Center of Emphasis, Pfizer Worldwide Research & Development, Cambridge, MA 02140, USA, 2Department of Mathematics, University of Massachusetts Boston, Boston, MA 02125, USA, 3Drug Safety Research & Development, Pfizer, Groton, CT 06340, USA and 4Neusentis, Pfizer Worldwide Research & Development, Cambridge CB21 6GS, UK

Funder

NIH

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

Reference21 articles.

1. A general modular framework for gene set enrichment analysis;Ackermann;BMC Bioinformatics,2009

2. Going Bayesian: model-based gene set analysis of genome-scale data;Bauer;Nucleic Acids Res.,2010

3. Causal reasoning on biological networks: interpreting transcriptional changes;Chindelevitch;Bioinformatics,2012

4. T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity;Costigan;J. Neurosci.,2009

5. Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic beta-cell line and mouse islets;da Silva Krause;J. Endocrinol.,2012

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