Affiliation:
1. Philip Morris Products S.A, PMI R&D, Neuchâtel CH, Switzerland
Abstract
Abstract
Summary
GladiaTOX R package is an open-source, flexible solution to high-content screening data processing and reporting in biomedical research. GladiaTOX takes advantage of the ‘tcpl’ core functionalities and provides a number of extensions: it provides a web-service solution to fetch raw data; it computes severity scores and exports ToxPi formatted files; furthermore it contains a suite of functionalities to generate PDF reports for quality control and data processing.
Availability and implementation
GladiaTOX R package (bioconductor). Also available via: git clone https://github.com/philipmorrisintl/GladiaTOX.git.
Supplementary information
Supplementary data are available at Bioinformatics online.
Funder
Philip Morris International
Publisher
Oxford University Press (OUP)
Subject
Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability
Reference6 articles.
1. An automated fitting procedure and software for dose-response curves with multiphasic features;Di Veroli;Sci. Rep,2015
2. tcpl: the ToxCast pipeline for high-throughput screening data;Filer;Bioinformatics,2017
3. HTS navigator: freely accessible cheminformatics software for analyzing high-throughput screening data;Fourches;Bioinformatics,2014
4. High content screening analysis to evaluate the toxicological effects of harmful and potentially harmful constituents (HPHC);Marescotti;J. Vis. Exp,2016
5. ToxPi Graphical User Interface 2.0: dynamic exploration, visualization, and sharing of integrated data models;Marvel;BMC Bioinformatics,2018
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献