PatientExploreR: an extensible application for dynamic visualization of patient clinical history from electronic health records in the OMOP common data model

Author:

Glicksberg Benjamin S1ORCID,Oskotsky Boris1,Thangaraj Phyllis M234,Giangreco Nicholas234ORCID,Badgeley Marcus A5ORCID,Johnson Kipp W5,Datta Debajyoti1,Rudrapatna Vivek A16,Rappoport Nadav1,Shervey Mark M5,Miotto Riccardo5,Goldstein Theodore C1,Rutenberg Eugenia1,Frazier Remi7,Lee Nelson7,Israni Sharat1,Larsen Rick7,Percha Bethany5,Li Li5,Dudley Joel T5,Tatonetti Nicholas P234,Butte Atul J18

Affiliation:

1. Bakar Computational Health Sciences Institute, University of California, San Francisco, San Francisco, CA, USA

2. Department of Biomedical Informatics, Columbia University, New York, NY, USA

3. Department of Systems Biology, Columbia University, New York, NY, USA

4. Department of Medicine, Columbia University, New York, NY, USA

5. Departments of Genomics and Data Science, Icahn Institute for Genomic Sciences and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Institute of Next Generation Healthcare, New York, NY, USA

6. Division of Gastroenterology, Department of Medicine, University of California, San Francisco, CA, USA

7. Enterprise Information and Analytics, University of California, San Francisco, San Francisco, CA, USA

8. Center for Data-Driven Insights and Innovation, University of California Health, Oakland, CA, USA

Abstract

AbstractMotivationElectronic health records (EHRs) are quickly becoming omnipresent in healthcare, but interoperability issues and technical demands limit their use for biomedical and clinical research. Interactive and flexible software that interfaces directly with EHR data structured around a common data model (CDM) could accelerate more EHR-based research by making the data more accessible to researchers who lack computational expertise and/or domain knowledge.ResultsWe present PatientExploreR, an extensible application built on the R/Shiny framework that interfaces with a relational database of EHR data in the Observational Medical Outcomes Partnership CDM format. PatientExploreR produces patient-level interactive and dynamic reports and facilitates visualization of clinical data without any programming required. It allows researchers to easily construct and export patient cohorts from the EHR for analysis with other software. This application could enable easier exploration of patient-level data for physicians and researchers. PatientExploreR can incorporate EHR data from any institution that employs the CDM for users with approved access. The software code is free and open source under the MIT license, enabling institutions to install and users to expand and modify the application for their own purposes.Availability and implementationPatientExploreR can be freely obtained from GitHub: https://github.com/BenGlicksberg/PatientExploreR. We provide instructions for how researchers with approved access to their institutional EHR can use this package. We also release an open sandbox server of synthesized patient data for users without EHR access to explore: http://patientexplorer.ucsf.edu.Supplementary informationSupplementary data are available at Bioinformatics online.

Funder

National Center for Advancing Translational Sciences

National Institutes of Health

NIH

Bakar Computational Health Sciences Institute

National Institute of Diabetes and Digestive and Kidney Disease

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

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