SANDPUMA: ensemble predictions of nonribosomal peptide chemistry reveal biosynthetic diversity across Actinobacteria

Author:

Chevrette Marc G12,Aicheler Fabian3,Kohlbacher Oliver34,Currie Cameron R2,Medema Marnix H5

Affiliation:

1. Department of Genetics, University of Wisconsin-Madison, Madison, WI, USA

2. Department of Bacteriology and J. F. Crow Institute for the Study of Evolution, University of Wisconsin-Madison, Madison, WI, USA

3. Applied Bioinformatics, Department of Computer Science, Quantitative Biology Center and Center for Bioinformatics, University of Tübingen, Tübingen, Germany

4. Biomolecular Interactions, Max Planck Institute for Developmental Biology, Tübingen, Germany

5. Bioinformatics Group, Wageningen University, Wageningen, The Netherlands

Funder

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

Reference46 articles.

1. Predicting substrate specificity of adenylation domains of nonribosomal peptide synthetases and other protein properties by latent semantic indexing;Baranašić;J. Ind. Microbiol. Biotechnol,2014

2. antiSMASH 4.0––improvements in chemistry prediction and gene cluster boundary identification;Blin;Nucleic Acids Res,2017

3. Fast and sensitive protein alignment using DIAMOND;Buchfink;Nat. Methods,2015

4. Diversity of monomers in nonribosomal peptides: towards the prediction of origin and biological activity;Caboche;J. Bacteriol,2010

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