An approachable, flexible and practical machine learning workshop for biologists

Author:

Magnano Chris S12,Mu Fangzhou2,Russ Rosemary S3,Cvetkovic Milica4,Treu Debora1,Gitter Anthony125

Affiliation:

1. Morgridge Institute for Research , Madison, WI 53715, USA

2. Department of Computer Sciences, University of Wisconsin-Madison , Madison, WI 53706, USA

3. Department of Curriculum and Instruction, University of Wisconsin-Madison , Madison, WI 53715, USA

4. Department of Statistics, University of Wisconsin-Madison , Madison, WI 53706, USA

5. Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison , Madison, WI 53706, USA

Abstract

Abstract Summary The increasing prevalence and importance of machine learning in biological research have created a need for machine learning training resources tailored towards biological researchers. However, existing resources are often inaccessible, infeasible or inappropriate for biologists because they require significant computational and mathematical knowledge, demand an unrealistic time-investment or teach skills primarily for computational researchers. We created the Machine Learning for Biologists (ML4Bio) workshop, a short, intensive workshop that empowers biological researchers to comprehend machine learning applications and pursue machine learning collaborations in their own research. The ML4Bio workshop focuses on classification and was designed around three principles: (i) emphasizing preparedness over fluency or expertise, (ii) necessitating minimal coding and mathematical background and (iii) requiring low time investment. It incorporates active learning methods and custom open-source software that allows participants to explore machine learning workflows. After multiple sessions to improve workshop design, we performed a study on three workshop sessions. Despite some confusion around identifying subtle methodological flaws in machine learning workflows, participants generally reported that the workshop met their goals, provided them with valuable skills and knowledge and greatly increased their beliefs that they could engage in research that uses machine learning. ML4Bio is an educational tool for biological researchers, and its creation and evaluation provide valuable insight into tailoring educational resources for active researchers in different domains. Availability and implementation Workshop materials are available at https://github.com/carpentries-incubator/ml4bio-workshop and the ml4bio software is available at https://github.com/gitter-lab/ml4bio. Supplementary information Supplementary data are available at Bioinformatics online.

Funder

National Institutes of Health

National Science Foundation

Morgridge Institute for Research and the University of Wisconsin-Madison Office of the Vice Chancellor for Research and Graduate Education

Wisconsin Alumni Research Foundation

Publisher

Oxford University Press (OUP)

Subject

Computational Mathematics,Computational Theory and Mathematics,Computer Science Applications,Molecular Biology,Biochemistry,Statistics and Probability

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