qPTMplants: an integrative database of quantitative post-translational modifications in plants

Author:

Xue Han1ORCID,Zhang Qingfeng2,Wang Panqin1,Cao Bijin1,Jia Chongchong1,Cheng Ben1,Shi Yuhua1,Guo Wei-Feng3,Wang Zhenlong1,Liu Ze-Xian2ORCID,Cheng Han1ORCID

Affiliation:

1. School of Life Sciences, Zhengzhou University, Zhengzhou 450001, China

2. State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou 510060, China

3. School of Electrical Engineering, Zhengzhou University, Zhengzhou 450001, China

Abstract

Abstract As a crucial molecular mechanism, post-translational modifications (PTMs) play critical roles in a wide range of biological processes in plants. Recent advances in mass spectrometry-based proteomic technologies have greatly accelerated the profiling and quantification of plant PTM events. Although several databases have been constructed to store plant PTM data, a resource including more plant species and more PTM types with quantitative dynamics still remains to be developed. In this paper, we present an integrative database of quantitative PTMs in plants named qPTMplants (http://qptmplants.omicsbio.info), which hosts 1 242 365 experimentally identified PTM events for 429 821 nonredundant sites on 123 551 proteins under 583 conditions for 23 PTM types in 43 plant species from 293 published studies, with 620 509 quantification events for 136 700 PTM sites on 55 361 proteins under 354 conditions. Moreover, the experimental details, such as conditions, samples, instruments and methods, were manually curated, while a variety of annotations, including the sequence and structural characteristics, were integrated into qPTMplants. Then, various search and browse functions were implemented to access the qPTMplants data in a user-friendly manner. Overall, we anticipate that the qPTMplants database will be a valuable resource for further research on PTMs in plants.

Funder

National Natural Science Foundation of China

Guangdong Innovative and Entrepreneurial Research Team Program

Tip-top Scientific and Technical Innovative Youth Talents of Guangdong Special Support Program

Key Scientific and Technological Projects of Henan Province

China Postdoctoral Research Foundation

Henan Postdoctoral Foundation

Publisher

Oxford University Press (OUP)

Subject

Genetics

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