Locus-specific transcription silencing at the FHIT gene suppresses replication stress-induced copy number variant formation and associated replication delay
Author:
Affiliation:
1. Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA
2. Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
3. Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA
Abstract
Funder
National Institutes of Health
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/49/13/7507/39117049/gkab559.pdf
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3. Hydroxyurea induces de novo copy number variants in human cells;Arlt;Proc. Natl. Acad. Sci. U.S.A.,2011
4. Copy number variants are produced in response to low-dose ionizing radiation in cultured cells;Arlt;Environ. Mol. Mutagen.,2014
5. Large transcription units unify copy number variants and common fragile sites arising under replication stress;Wilson;Genome Res.,2015
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