piRBase: integrating piRNA annotation in all aspects-Reference-Cited by-同舟云学术

piRBase: integrating piRNA annotation in all aspects

Published:2021-12-06 Issue:D1 Volume:50 Page:D265-D272
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Wang Jiajia¹²³⁴,Shi Yirong³⁵,Zhou Honghong¹²³,Zhang Peng³⁶^ORCID,Song Tingrui³,Ying Zhiye¹²,Yu Haopeng¹²,Li Yanyan¹²³,Zhao Yi¹²⁷^ORCID,Zeng Xiaoxi¹²,He Shunmin¹²³⁴⁶^ORCID,Chen Runsheng¹²³⁶⁸

Affiliation:

1. West China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu 610041, China

2. Med-X Center for Informatics, Sichuan University, Chengdu 610041, China

3. Key Laboratory of RNA Biology, Center for Big Data Research in Health, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China

4. College of Life Sciences, University of Chinese Academy of Sciences, Beijing 100049, China

5. University of Chinese Academy of Sciences, Beijing 100049, China

6. National Genomics Data Center, Chinese Academy of Sciences, Beijing 100101, China

7. Key Laboratory of Intelligent Information Processing, Advanced Computer Research Center, Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100190, China

8. Guangdong Geneway Decoding Bio-Tech Co. Ltd, Foshan 528316, China

Abstract

Abstract Piwi-interacting RNAs are a type of small noncoding RNA that have various functions. piRBase is a manually curated resource focused on assisting piRNA functional analysis. piRBase release v3.0 is committed to providing more comprehensive piRNA related information. The latest release covers >181 million unique piRNA sequences, including 440 datasets from 44 species. More disease-related piRNAs and piRNA targets have been collected and displayed. The regulatory relationships between piRNAs and targets have been visualized. In addition to the reuse and expansion of the content in the previous version, the latest version has additional new content, including gold standard piRNA sets, piRNA clusters, piRNA variants, splicing-junction piRNAs, and piRNA expression data. In addition, the entire web interface has been redesigned to provide a better experience for users. piRBase release v3.0 is free to access, browse, search, and download at http://bigdata.ibp.ac.cn/piRBase.

Funder

National Natural Science Foundation of China

Strategic Priority Research Program of Chinese Academy of Sciences

National Key Research and Development Program of China

West China Hospital, Sichuan University

Research Fund for Academician Workstation

Chinese Academy of Sciences

Ministry of Science and Technology, China

National Genomics Data Center, China

Publisher

Oxford University Press (OUP)

Subject