Whole Genome Sequencing of a Methicillin-Resistant Staphylococcus aureus Pseudo-Outbreak in a Professional Football Team

Author:

Anderson Deverick J.1,Harris Simon R.2,Godofsky Eliot3,Toriscelli Todd4,Rude Thomas H.1,Elder Kevin56,Sexton Daniel J.1,Pellman Elliot J.78,Mayer Thom910,Fowler Vance G.1,Peacock Sharon J.11

Affiliation:

1. Duke University Medical Center, Durham, North Carolina

2. Wellcome Trust Sanger Institute, Hinxton, United Kingdom

3. Bach & Godofsky, Bradenton, Florida

4. St. Thomas Sports Park, Nashville, Tennessee

5. BayCare Medical Group

6. University of South Florida, Tampa

7. Icahn School of Medicine at Mount Sinai

8. ProHEALTH Care Associates LLP, New York, New York

9. George Washington University School of Medicine, District of Columbia

10. University of Virginia School of Medicine, Charlottesville

11. University of Cambridge, United Kingdom

Abstract

Abstract Two American football players on the same team were diagnosed with methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections on the same day. Our investigation, including whole genome sequencing, confirmed that players did not transmit MRSA to one another nor did they acquire the MRSA from a single source within the training facility.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Oncology

Reference12 articles.

1. Methicillin-resistant S. aureus infections among patients in the emergency department;Moran;N Engl J Med,2006

2. Methicillin-resistant Staphylococcus aureus among players on a high school football team--New York City, 2007;Centers for Disease Control and Prevention (CDC);MMWR Morb Mortal Wkly Rep,2009

3. A clone of methicillin-resistant Staphylococcus aureus among professional football players;Kazakova;N Engl J Med,2005

4. Whole-genome sequencing for analysis of an outbreak of methicillin-resistant Staphylococcus aureus: a descriptive study;Harris;Lancet Infect Dis,2013

5. Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak;Koser;N Engl J Med,2012

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