DNA mismatch repair gene MSH6 implicated in determining age at natural menopause

Author:

Perry John R.B.1234,Hsu Yi-Hsiang56,Chasman Daniel I.78,Johnson Andrew D.910,Elks Cathy4,Albrecht Eva11,Andrulis Irene L.1213,Beesley Jonathan14,Berenson Gerald S.15,Bergmann Sven1617,Bojesen Stig E.18,Bolla Manjeet K.19,Brown Judith19,Buring Julie E.78,Campbell Harry20,Chang-Claude Jenny21,Chenevix-Trench Georgia14,Corre Tanguy1617,Couch Fergus J.22,Cox Angela23,Czene Kamila24,D'adamo Adamo Pio25,Davies Gail262728,Deary Ian J.2627,Dennis Joe19,Easton Douglas F.19,Engelhardt Ellen G.29,Eriksson Johan G.3031323334,Esko Tõnu353637,Fasching Peter A.38,Figueroa Jonine D.39,Flyger Henrik40,Fraser Abigail41,Garcia-Closas Montse42,Gasparini Paolo25,Gieger Christian11,Giles Graham4344,Guenel Pascal45,Hägg Sara2446,Hall Per24,Hayward Caroline47,Hopper John43,Ingelsson Erik46,Kardia Sharon L.R.48,Kasiman Katherine24,Knight Julia A.12,Lahti Jari3249,Lawlor Debbie A.41,Magnusson Patrik K.E.24,Margolin Sara50,Marsh Julie A.51,Metspalu Andres37,Olson Janet E.52,Pennell Craig E.51,Polasek Ozren53,Rahman Iffat24,Ridker Paul M.78,Robino Antonietta25,Rudan Igor20,Rudolph Anja21,Salumets Andres5455,Schmidt Marjanka K.2956,Schoemaker Minouk J.42,Smith Erin N.57,Smith Jennifer A.48,Southey Melissa58,Stöckl Doris5960,Swerdlow Anthony J.42,Thompson Deborah J.19,Truong Therese45,Ulivi Sheila61,Waldenberger Melanie62,Wang Qin19,Wild Sarah20,Wilson James F20,Wright Alan F.28,Zgaga Lina20,Ong Ken K.463,Murabito Joanne M.964,Karasik David5,Murray Anna1, ,

Affiliation:

1. University of Exeter Medical School, Exeter, UK,

2. Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK,

3. Department of Twin Research and Genetic Epidemiology, King's College London, London, UK,

4. Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK,

5. Hebrew SeniorLife Institute for Aging Research and Harvard Medical School, Boston, MA, USA,

6. Molecular and Integrative Physiological Sciences Program, Harvard School of Public Health, Boston, MA, USA,

7. Division of Preventive Medicine, Brigham and Women's Hospital, 900 Commonwealth Avenue East, Boston MA 02215, USA,

8. Harvard Medical School, Boston, MA, USA,

9. The National Heart Lung and Blood Institute's Framingham Heart Study, Framingham, MA, USA,

10. NHLBI Cardiovascular Epidemiology & Human Genomics Branch, Bethesda, MD, USA,

11. Institute of Genetic Epidemiology,

12. Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada,

13. Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada,

14. Department of Genetics, Queensland Institute of Medical Research, Brisbane, QLD, Australia,

15. Department of Epidemiology, Tulane University, New Orleans, LA, USA,

16. Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland,

17. Swiss Institute of Bioinformatics, Lausanne, Switzerland,

18. Department of Clinical Biochemistry and the Copenhagen General Population Study, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark,

19. Centre for Cancer Genetic Epidemiology and Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK,

20. Centre for Population Health Sciences, University of Edinburgh, EdinburghEH8 9AG, UK,

21. Division of Cancer Epidemiology, German Cancer Research Center, Heidelberg, Germany,

22. Departments of Laboratory Medicine and Pathology, and Health Science Research,

23. CR-UK/YCR Sheffield Cancer Research Centre, Department of Oncology, University of Sheffield, UK,

24. Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden,

25. Institute for Maternal and Child Health, IRCCS ‘Burlo Garofolo’, University of Trieste, Trieste, Italy,

26. Centre for Cognitive Ageing and Cognitive Epidemiology,

27. Department of Psychology and

28. MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK,

29. Division of Psychosocial Research and Epidemiology and

30. Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland,

31. National Institute for Health and Welfare, Helsinki, Finland,

32. Folkhälsan Research Centre, Helsinki, Finland,

33. University Central Hospital, Unit of General Practice, Helsinki, Finland,

34. Vasa Central Hospital, Vasa, Finland,

35. Divisions of Endocrinology, Children's Hospital, Boston, MA, USA,

36. Broad Institute, Cambridge, MA, USA,

37. Estonian Genome Center, University of Tartu, 51010Tartu, Estonia,

38. Department of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany,

39. Division of Cancer Epidemiology & Genetics, National Cancer Institute, Maryland, USA,

40. Department of Breast Surgery, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark,

41. School of Social and Community Medicine, MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK,

42. Divisions of Breast Cancer Research and of Genetics and Epidemiology, and the Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, London, UK,

43. Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, Melbourne School of Population Health, The University of Melbourne, Melbourne, VIC, Australia,

44. Cancer Epidemiology Centre, The Cancer Council Victoria, Melbourne, VIC, Australia,

45. Environmental Epidemiology of Cancer, Inserm U1018, Villejuif, France,

46. Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden,

47. Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, EdinburghEH4 2XU, UK,

48. Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA,

49. Institute of Behavioural Science, University of Helsinki, Helsinki, Finland,

50. Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden,

51. School of Women's and Infants’ Health, University of Western Australia, Australia,

52. Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA,

53. Department of Public Health, Faculty of Medicine, University of Split, Croatia,

54. Department of Obstetrics and Gynecology, University of Tartu, 51014 Tartu, Estonia,

55. Competence Centre on Reproductive Medicine and Biology, 50410 Tartu, Estonia,

56. Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands,

57. Department of Pediatrics and Rady Children's Hospital, University of California San Diego, La Jolla, CA 92093, USA,

58. Genetic Epidemiology Laboratory, Department of Pathology, The University of Melbourne, Melbourne, VIC, Australia,

59. Institute of Epidemiology II and

60. Department of Obstetrics and Gynaecology, Campus Grosshadern, Ludwig-Maximilians-University, Munich, Germany,

61. Institute for Maternal and Child Health, IRCCS ‘Burlo Garofolo’, Trieste, Italy,

62. Research Unit of Molecular Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health, Neuherberg, Germany,

63. Department of Paediatrics, University of Cambridge, Cambridge, UK,

64. Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

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