Platycarya strobilacea Sieb. et Zucc.: a review of its traditional uses, botany, phytochemistry, pharmacology and toxicology

Author:

Zhao Peiyuan1ORCID,Han Lizhu1,Wang Yunlan1,Qiu Jinqing1,Zhang Xinbo1,Tang Zhishu1,Duan Xi2,Song Xiao1ORCID

Affiliation:

1. School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang, China

2. Affiliated Hospital, Shaanxi University of Chinese Medicine, Xianyang, China

Abstract

Abstract Objectives Platycarya strobilacea Sieb. et Zucc. is the dry infructescence of P. strobilacea, a Juglandaceae plant and is a traditional Chinese medicine with great development potential and utilization value. This study summarizes the research progress on the traditional uses, botany, phytochemistry, extraction methods, pharmacology and toxicology of Platycarya strobilacea Sieb. et Zucc., and provides potential therapeutic uses and drug development prospects for this plant. Key findings Phytochemical studies showed that this plant mainly contains volatile constituents, phenols, terpenoids and a carbohydrate. The pharmacological activity of Platycarya strobilacea Sieb. et Zucc. includes antibacterial and anti-inflammatory effects, anti-tumour effects and antioxidant effects. This plant is especially effective in the treatment of allergic rhinitis and chronic sinusitis. Summary In this review, the phytochemistry and pharmacological effects of Platycarya strobilacea Sieb. et Zucc. are described in detail, which will have guiding significance for the future development of this drug.

Funder

National Key Research and Development Program for Traditional Chinese Medicine Modernization

Project of Shaanxi Provincial Education Department

Project of Shaanxi Provincial Department of Science and Technology

Shaanxi Provincial Key Laboratory of TCM Foundation and New Drug Research

Shaanxi Key Discipline of Traditional Chinese Medicine Pharmacy

Publisher

Oxford University Press (OUP)

Subject

Pharmaceutical Science,Pharmacology

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