Perspective: Creating the Evidence Base for Nutritional Support in Childhood Cancer in Low- and Middle-Income Countries: Priorities for Body Composition Research

Author:

Murphy-Alford Alexia J1ORCID,Prasad Maya2,Slone Jeremy3,Stein Katja4,Mosby Terezie T5

Affiliation:

1. Nutritional and Health-Related Environmental Studies Section, International Atomic Energy Agency, Vienna, Austria

2. Department of Medical Oncology, Tata Memorial Hospital, Mumbai, India

3. Baylor College of Medicine/Texas Children's Hospital, Houston, TX, USA

4. Civil Hospital of Guadalajara Dr Juan I Menchaca, University Center of Health Sciences, University of Guadalajara, Guadalajara, Mexico

5. Department of Food Science, Nutrition and Health Promotion, Mississippi State University, Mississippi State, MS, USA

Abstract

ABSTRACT There is a striking disparity in survival rates for children in low- and middle-income countries (LMICs) compared with high-income countries (HICs). Many of the contributing factors are preventable, including the comorbidity of malnutrition. There are emerging data that malnutrition, as reflected in body composition changes, impacts survival of cancer. However, not enough priority is given to nutrition management of children with cancer, particularly in LMICs. The primary purpose of this article is to review the current knowledge on childhood cancer and body composition in LMICs and identify priorities for future research into the interlinking associations between cancer, body composition, and clinical outcomes for childhood cancer patients. Evidence will ensure feasible and effective nutrition management is prioritized in childhood cancer centers in LMICs and contribute to improving outcomes for children with cancer.

Publisher

Oxford University Press (OUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous),Food Science

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