Urine-derived stem cells: applications in skin, bone and articular cartilage repair-Reference-Cited by-同舟云学术

Urine-derived stem cells: applications in skin, bone and articular cartilage repair

Published:2021-01-01 Issue: Volume:9 Page:
ISSN:2321-3876
Container-title:Burns & Trauma
language:en
Short-container-title:

Author:

Zhang Wenqian¹^ORCID,Hu Jungen¹,Huang Yizhou¹,Wu Chenyu¹,Xie Huiqi¹

Affiliation:

1. Laboratory of Stem Cell and Tissue Engineering, Orthopedic Research Institute, Med-X Center for Materials, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

Abstract

Abstract As an emerging type of adult stem cell featuring non-invasive acquisition, urine-derived stem cells (USCs) have shown great potential for applications in tissue engineering and regenerative medicine. With a growing amount of research on the topic, the effectiveness of USCs in various disease models has been shown and the underlying mechanisms have also been explored, though many aspects still remain unclear. In this review, we aim to provide an up-to-date overview of the biological characteristics of USCs and their applications in skin, bone and articular cartilage repair. In addition to the identification procedure of USCs, we also summarize current knowledge of the underlying repair mechanisms and application modes of USCs. Potential concerns and perspectives have also been summarized.

Funder

1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University

National Natural Science Foundation of China

Publisher

Oxford University Press (OUP)

Subject

Critical Care and Intensive Care Medicine,Dermatology,Biomedical Engineering,Emergency Medicine,Immunology and Allergy,Surgery

Link

https://academic.oup.com/burnstrauma/article-pdf/doi/10.1093/burnst/tkab039/42005538/tkab039.pdf

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