Insensitivity of the in vitro cytokinesis-block micronucleus assay with human lymphocytes for the detection of DNA damage present at the start of the cell culture-Reference-Cited by-同舟云学术

Insensitivity of the in vitro cytokinesis-block micronucleus assay with human lymphocytes for the detection of DNA damage present at the start of the cell culture

Published:2012-08-06 Issue:6 Volume:27 Page:743-747
ISSN:0267-8357
Container-title:Mutagenesis
language:en
Short-container-title:Mutagenesis

Author:

Speit G.,Linsenmeyer R.,Schutz P.,Kuehner S.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Genetics(clinical),Toxicology,Genetics

Link

http://academic.oup.com/mutage/article-pdf/27/6/743/3674062/ges041.pdf

Reference12 articles.

1. IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans

2. Cytokinesis-block micronucleus cytome assay

3. The in vivo or ex vivo origin of micronuclei measured in human biomonitoring studies

4. Inclusion of micronuclei in non-divided mononuclear lymphocytes and necrosis/apoptosis may provide a more comprehensive cytokinesis block micronucleus assay for biomonitoring purposes

5. Micronuclei in peripheral blood from patients after cytostatic therapy mainly arise ex vivo from persistent damage

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