In silico model for mutagenicity (Ames test), taking into account metabolism-Reference-Cited by-同舟云学术

In silico model for mutagenicity (Ames test), taking into account metabolism

Published:2019-01 Issue:1 Volume:34 Page:41-48
ISSN:0267-8357
Container-title:Mutagenesis
language:en
Short-container-title:

Author:

Vian Matteo¹,Raitano Giuseppa,Roncaglioni Alessandra¹,Benfenati Emilio¹

Affiliation:

1. Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Giuseppe La Masa, Milan, Italy

Funder

Project JANUS

Project LIFE-VERMEER

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Genetics (clinical),Toxicology,Genetics

Link

http://academic.oup.com/mutage/article-pdf/34/1/41/28015907/gey045.pdf

Reference26 articles.

1. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test;Ames;Mutat. Res.,1975

2. Alternatives to the carcinogenicity bioassay: in silico methods, and the in vitro and in vivo mutagenicity assays;Benigni;Expert Opin. Drug Metab. Toxicol.,2010

3. Organization for Economic Co-operation and Development guideline for testing of the chemicals, n.471, bacterial reverse mutation test. Commission Regulation (EC) No 440/2008. http://www.oecd.org/chemicalsafety/assessmentofchemicals/1948418.pdf

4. The Ames Salmonella/microsome mutagenicity assay;Mortelmans;Mutat. Res.,2000

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