Vertical Transmission of Hepatitis C Virus Among Women With a History of Injection Opioid Use

Author:

Cafardi John M1ORCID,Lin Hong T2,Lange Lana3,Kelley Lacey4,Lemon Kelly5,Odegard Elizabeth A2,Meeds Heidi L2,Blackard Jason T2,Feinberg Judith6

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, The Christ Hospital and the Lindner Research Institute , Cincinnati, Ohio , USA

2. Division of Digestive Diseases, Department of Internal Medicine, University of Cincinnati College of Medicine , Cincinnati, Ohio , USA

3. Department of Gynecology and Obstetrics, The Christ Hospital , Cincinnati, Ohio , USA

4. Department of Behavioral Medicine and Psychiatry, West Virginia University School of Medicine , Morgantown, West Virginia , USA

5. Department of Gynecology and Obstetrics, West Virginia University School of Medicine , Morgantown, West Virginia , USA

6. Departments of Behavioral Medicine and Psychiatry & Medicine/Infectious Diseases, West Virginia University School of Medicine , Morgantown, West Virginia , USA

Abstract

Abstract We evaluated vertical transmission and linkage to care in women with hepatitis C virus (HCV) and history of injection drug use employing co-localized testing and treatment. Transmission occurred in 1 of 23 infants, with mother-infant genetic distance of 1.26%. Rates for infant testing, maternal linkage, and cure were 77%, 52%, and 100%, respectively.

Funder

Gilead Sciences

Publisher

Oxford University Press (OUP)

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