Association Between Causative Pathogen and Occurrence of Infection-Related Glomerulonephritis in Infective Endocarditis

Author:

Shrestha Nabin K1ORCID,Kanyo Emese C2,Nakhoul Georges N3,Herlitz Leal C4,Gordon Steven M1

Affiliation:

1. Department of Infectious Diseases, Cleveland Clinic , Cleveland, Ohio , USA

2. Cleveland Clinic Lerner College of Medicine, Cleveland Clinic , Cleveland, Ohio , USA

3. Department of Kidney Medicine, Cleveland Clinic , Cleveland, Ohio , USA

4. Department of Pathology and Laboratory Medicine, Cleveland Clinic , Cleveland, Ohio , USA

Abstract

Abstract Among patients with pathologically proven infective endocarditis, the association of pathogen with occurrence of infection-related glomerulonephritis (IRGN) was examined in 48 case patients with IRGN and 192 propensity score-matched controls. Bartonella was very strongly associated with IRGN (odds ratio, 38.2 [95% confidence interval, 6.7–718.8]; P < .001); other microorganisms were not.

Publisher

Oxford University Press (OUP)

Reference12 articles.

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3. Glomerulonephritis in bacterial endocarditis;Neugarten;Am J Med,1984

4. The effect of penicillin on the renal lesions of subacute bacterial endocarditis;Spain;Ann Intern Med,1952

5. Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis–Prospective Cohort Study;Murdoch;Arch Intern Med,2009

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