Compared Performance of the 2023 Duke–International Society for Cardiovascular Infectious Diseases, 2000 Modified Duke, and 2015 European Society of Cardiology Criteria for the Diagnosis of Infective Endocarditis in a French Multicenter Prospective Cohort

Author:

Goehringer Francois1ORCID,Lalloué Benoit2,Selton-Suty Christine3ORCID,Alla François45ORCID,Botelho-Nevers Elisabeth67,Chirouze Catherine89,Curlier Elodie10,El Hatimi Safwane11,Gagneux-Brunon Amandine67ORCID,le Moing Vincent1213,Lim Pascal14ORCID,Piroth Lionel1516,Strady Christophe17,Tribouilloy Christophe1819ORCID,Virion Jean-Marc2,Agrinier Nelly2ORCID,Duval Xavier20212223,Hoen Bruno24ORCID, ,Agrinier Nelly,Alla François,Béraud Guillaume,Botelho-Nevers Elisabeth,Boutoille David,Chirouze Catherine,Delahaye François,Duval Xavier,Goehringer François,Hoen Bruno,Iung Bernard,Le Moing Vincent,Suty Christine Selton,Strady Christophe,Tattevin Pierre,Alauzet Corentine,Assayag Patrick,Azarnoush Kasra,Blot Mathieu,Bohbot Yohann,Bouiller Kevin,Buisson Marielle,Curlier Elodie,Dorigo Enrica,Duong Michel,Elfarra Mazen,Esteve Clémentine,Filippetti Laura,Fournier Damien,Grand Nathalie,Huguet Raphaëlle,Ilic-Habensus Emila,Le Bot Audrey,Lefèvre Benjamin,Lepeule Raphaël,Mahy Sophie,Monnin Charles,Mouhat Basile,Noël Franck,Pansu Nathalie,Perez Lucas,Petrosyan Andranik,Pierrard Romain,Revest Matthieu,Sixt Thibault,Suzat Anne,Tassigny Charles,Tissot Noémie,Aboudaoud Dehbia,Bouguerra Hassina,Campagnac Catherine,Charles Carole,Corradi Giulia,Dupuy Sandra,Francius Eola,Gerset Sandrine,Gohier Sandrine,Gun Mesut,André Maryse,Ronat Véronique,Albayrak Tubanur Unal,Erpelding Marie-Line,Juge Nadine,Lalloué Benoit,Sime Willy Ngueyon,Sponga Marie,Virion Jean-Marc

Affiliation:

1. Service de maladies infectieuses et tropicales, CHRU de Nancy , Nancy , France

2. CHRU de Nancy, INSERM, CIC, Epidémiologie Clinique, Université de Lorraine , Nancy , France

3. Département de cardiologie médicale, CHRU de Nancy, CIC-EC , Nancy , France

4. INSERM, BPH, U1219, I-prev/PHARES, CIC 1401, Universite Bordeaux , Bordeaux , France

5. Service de prévention, CHU de Bordeaux , Bordeaux , France

6. Service de maladies infectieuses, CHU de Saint-Etienne , Saint-Etienne , France

7. CIRI—Centre International de Recherche en Infectiologie, Team GIMAP, Université Jean Monnet, Université de Lyon, Inserm, U1111, CNRS, UMR530 , Saint-Etienne , France

8. Chrono-environnement UMR6249, CNRS, Université de Bourgogne Franche-Comté , Besançon , France

9. Service de maladies infectieuses et tropicales, CHU Jean Minjoz , Besançon , France

10. Service de maladies infectieuses, CHU de la Guadeloupe , Pointe-à-Pitre , France

11. CHU Bicêtre, Université Paris Saclay , Le Kremlin Bicêtre , France

12. Service de Maladies Infectieuses et Tropicales, CHU de Montpellier , Montpellier , France

13. Université de Montpellier , Montpellier , France

14. Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpitaux Universitaires Henri Mondor, Faculté de Santé, Univ. Paris Est Créteil , Créteil , France

15. Service de maladies infectieuses, CHU de Dijon , Dijon , France

16. CHU Dijon-Bourgogne, INSERM, CIC 1432, Module Épidémiologie Clinique, Université de Bourgogne , Dijon , France

17. Cabinet d'infectiologie, Groupe Courlancy , Reims , France

18. UR UPJV 7517, Université Jules Verne , Amiens , France

19. CHU Amiens-Picardie , Amiens , France

20. Inserm CIC 1425 , Paris , France

21. Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Bichat Claude-Bernard , Paris , France

22. Inserm UMR-1137 IAME , Paris , France

23. UFR de Médecine-Bichat, Université Paris Cité , Paris , France

24. Ecole de santé publique—UR 4360 Apemac, Université de Lorraine , Nancy , France

Abstract

Abstract Background The 2023 Duke–International Society for Cardiovascular Diseases (ISCVID) criteria for infective endocarditis (IE) were proposed as an updated diagnostic classification of IE. Using an open prospective multicenter cohort of patients treated for IE, we compared the performance of these new criteria to that of the 2000 Modified Duke and 2015 European Society of Cardiology (ESC) criteria. Methods Cases of patients treated for IE between January 2017 and October 2022 were adjudicated as certain IE or not. Each case was also categorized as either definite or possible/rejected within each classification. Sensitivity, specificity, and accuracy were estimated with 95% confidence intervals. Results Of the 1194 patients analyzed (mean age, 66.1 years; 71.2% males), 414 (34.7%) had a prosthetic valve and 284 (23.8%) had a cardiac implanted electronic device (CIED); 946 (79.2%) were adjudicated as certain IE; 978 (81.9%), 997 (83.5%), and 1057 (88.5%) were classified as definite IE in the 2000 modified Duke, 2015 ESC, and 2023 Duke–ISCVID criteria, respectively. The sensitivity of each set of criteria was 93.2% (95% confidence interval [CI], 91.6–94.8), 95.0% (95% CI, 93.7–96.4), and 97.6% (95% CI, 96.6–98.6), respectively (P < .001 for all 2-by-2 comparisons). Corresponding specificity rates were 61.3% (95% CI, 55.2–67.4), 60.5% (95% CI, 54.4–66.6), and 46.0% (95% CI, 39.8–52.2), respectively. In patients without CIED, sensitivity rates were 94.8% (95% CI, 93.2–96.4), 96.5% (95% CI, 95.1–97.8), and 97.7% (95% CI, 96.6–98.8); specificity rates were 59.0% (95% CI, 51.6–66.3), 56.6% (95% CI, 49.3–64.0), and 53.8% (95% CI, 46.3–61.2), respectively. Conclusions Overall, the 2023 Duke–ISCVID criteria had a significantly higher sensitivity but a significantly lower specificity compared with older criteria. This decreased specificity was mainly attributable to patients with CIED.

Publisher

Oxford University Press (OUP)

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3