Opinion: uracil DNA glycosylase (UNG) plays distinct and non-canonical roles in somatic hypermutation and class switch recombination
Author:
Publisher
Oxford University Press (OUP)
Subject
Immunology,General Medicine,Immunology and Allergy
Link
http://academic.oup.com/intimm/article-pdf/26/10/575/9723206/dxu071.pdf
Reference33 articles.
1. The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination
2. Separate domains of AID are required for somatic hypermutation and class-switch recombination
3. C-Terminal Deletion of AID Uncouples Class Switch Recombination from Somatic Hypermutation and Gene Conversion
4. AID mutant analyses indicate requirement for class-switch-specific cofactors
5. DNA Deamination in Immunity: AID in the Context of Its APOBEC Relatives
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