Diversity of energy metabolism in immune responses regulated by micro-organisms and dietary nutrition-Reference-Cited by-同舟云学术

Diversity of energy metabolism in immune responses regulated by micro-organisms and dietary nutrition

Published:2020-03-27 Issue:7 Volume:32 Page:447-454
ISSN:1460-2377
Container-title:International Immunology
language:en
Short-container-title:

Author:

Hosomi Koji¹,Kunisawa Jun¹²³⁴

Affiliation:

1. Laboratory of Vaccine Materials, Center for Vaccine and Adjuvant Research, and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health, and Nutrition (NIBIOHN), Ibaraki City, Osaka, Japan

2. International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, University of Tokyo, Minato-ku, Tokyo, Japan

3. Graduate School of Medicine, Graduate School of Pharmaceutical Sciences, Graduate School of Density, Osaka University, Yamadaoka, Suita-shi, Osaka, Japan

4. Graduate School of Medicine, Kobe University, Tyuou-ku, Kobe-shi, Hyogo, Japan

Abstract

AbstractImmune metabolism has been recognized as a new paradigm in the regulation of host immunity. In the environment, there are many micro-organisms including pathogenic and non-pathogenic and/or beneficial ones. Immune cells exhibit various responses against different types of microbes, which seem to be associated with changes in energy metabolism. In addition, dietary nutrition influences host metabolism and consequent responses by immune cells. In this review, we describe the complex network of immune metabolism from the perspectives of nutrition, micro-organisms and host immunity for the control of immunologic health and diseases.

Funder

Ministry of Education, Culture, Sports, Science, and Technology of Japan

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Ministry of Health, Labour and Welfare

Science and Technology Research Promotion Program for Agriculture, Forestry, Fisheries, and Food Industry

Terumo Foundation for Life Sciences and Arts

ONO Medical Research Foundation

Canon Foundation in Europe

Cross-ministerial Strategic Innovation Promotion Program

Joint Research Project of the Institute of Medical Science, the University of Tokyo

Public/Private R&D Investment Strategic Expansion PrograM