Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa

Author:

Goodall Ruth L.1,Dunn David T.1,Nkurunziza Peter2,Mugarura Lincoln3,Pattery Theresa4,Munderi Paula3,Kityo Cissy3,Gilks Charles5,Kaleebu Pontiano3,Pillay Deenan67,Gupta Ravindra K.67,

Affiliation:

1. MRC CTU at UCL, London, UK

2. MRC/UVRI Uganda Research Unit on AIDS, Entebbe, Uganda

3. Joint Clinical Research Centre, Kampala, Uganda

4. Janssen Diagnostics, a division of Janssen Pharmaceuticals NV, Beerse, Belgium

5. School of Population Health, University of Queensland, Brisbane, Australia

6. Africa Health Research Institute, KwaZulu Natal, South Africa

7. Division of Infection and Immunity, University College London, London, UK

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

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