Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T-Cell Decline, and Per-Parasite Pathogenicity-Reference-Cited by-同舟云学术

Dissecting HIV Virulence: Heritability of Setpoint Viral Load, CD4+ T-Cell Decline, and Per-Parasite Pathogenicity

Published:2017-10-03 Issue:1 Volume:35 Page:27-37
ISSN:0737-4038
Container-title:Molecular Biology and Evolution
language:en
Short-container-title:

Author:

Bertels Frederic¹,Marzel Alex²³,Leventhal Gabriel¹,Mitov Venelin⁴,Fellay Jacques⁵,Günthard Huldrych F²³,Böni Jürg³,Yerly Sabine⁶,Klimkait Thomas⁷,Aubert Vincent⁸,Battegay Manuel⁹,Rauch Andri¹⁰,Cavassini Matthias¹¹,Calmy Alexandra¹²,Bernasconi Enos¹³,Schmid Patrick¹⁴,Scherrer Alexandra U²³,Müller Viktor¹⁵¹⁶,Bonhoeffer Sebastian¹,Kouyos Roger²³,Regoes Roland R¹,

Affiliation:

1. Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland

2. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland

3. Institute of Medical Virology, University of Zurich, Zurich, Switzerland

4. Department of Biosystems Science and Engineering, ETH Zurich, Zurich, Switzerland

5. School of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

6. Division of Infectious Diseases, Laboratory of Virology, Geneva University Hospital, Geneva, Switzerland

7. Molecular Virology, Department of Biomedicine – Petersplatz, University of Basel, Basel, Switzerland

8. Division of Immunology and Allergy, University Hospital Lausanne, Lausanne, Switzerland

9. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland

10. Department of Infectious Diseases, Berne University Hospital and University of Berne, Berne, Switzerland

11. Division of Infectious Diseases, University Hospital Lausanne, Lausanne, Switzerland

12. HIV/AIDS Unit, Infectious Disease Service, Geneva University Hospital, Geneva, Switzerland

13. Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland

14. Division of Infectious Diseases, Cantonal Hospital St Gallen, St Gallen, Switzerland

15. Institute of Biology, Eötvös Loránd University, Budapest, Hungary

16. Evolutionary Systems Research Group, MTA Centre for Ecological Research, Tihany, Hungary

Publisher

Oxford University Press (OUP)

Subject

Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Link

http://academic.oup.com/mbe/article-pdf/35/1/27/24367357/msx246.pdf

Reference60 articles.

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4. Parent-offspring regression to estimate the heritability of an HIV-1 trait in a realistic setup;Bachmann;Retrovirology,2017

5. HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 loads;Baeten;J Infect Dis,2007

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