Stability-Mediated Epistasis Restricts Accessible Mutational Pathways in the Functional Evolution of Avian Hemoglobin-Reference-Cited by-同舟云学术

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Stability-Mediated Epistasis Restricts Accessible Mutational Pathways in the Functional Evolution of Avian Hemoglobin

Published:2017-02-13 Issue:5 Volume:34 Page:1240-1251
ISSN:0737-4038
Container-title:Molecular Biology and Evolution
language:en
Short-container-title:

Author:

Kumar Amit,Natarajan Chandrasekhar,Moriyama Hideaki,Witt Christopher C.,Weber Roy E.,Fago Angela,Storz Jay F.

Publisher

Oxford University Press (OUP)

Subject

Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Link

http://academic.oup.com/mbe/article-pdf/34/5/1240/13636070/msx085.pdf

Reference89 articles.

1. Hemoglobin Indianapolis (β112[G14] arginine). An unstable β-chain variant producing the phenotype of severe β-thalassemia;J Clin Invest,1979

2. Structure of inositol-hexaphosphate-human deoxyhaemoglobin complex;Nature,1974

3. Haemoglobin: the structural changes related to ligand binding and its allosteric mechanism;J Mol Biol.,1979

4. On the (un)predictability of a large intragenic fitness landscape;Proc Natl Acad Sci U S A.,2016

5. The allosteric properties of hemoglobin: insights from natural and site directed mutants;Curr Protein Pept Sci,2006

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