Selection of targets and the most efficient hairpin ribozymes for inactivation of mRNAs using a self‐cleaving RNA library
Author:
Affiliation:
1. Instituto de Parasitología y Biomedicina ‘López‐Neyra’, CSIC Ventanilla 11 18001 Granada Spain
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1093/embo-reports/kve247
Reference15 articles.
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4. Extensive phosphorothioate substitution yields highly active and nuclease-resistant hairpin ribozymes
5. Substrate selection rules for the hairpin ribozyme determined by in vitro selection, mutation, and analysis of mismatched substrates.
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