Impact of changed co-amoxiclav susceptibility testing formats on apparent resistance rates for bloodstream Escherichia coli in a long-term surveillance

Author:

Reynolds Rosy1,Mushtaq Shazad2,Allen Michael K.3,Horner Carolyne4,Longshaw Christopher5,Livermore David M.6

Affiliation:

1. Bristol Medical School, University of Bristol, Bristol, UK

2. UK Health Security Agency, London, UK

3. Merck Sharp & Dohme (UK) Limited, London, UK

4. BSAC, Birmingham, UK

5. Shionogi B.V., London, UK

6. University of East Anglia, Norwich, UK

Funder

NIHR

University of Bristol

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology,Microbiology (medical)

Reference5 articles.

1. Survey, laboratory and statistical methods for the BSAC Resistance Surveillance Programmes;Reynolds;J Antimicrob Chemother,2008

2. Performance of EUCAST and CLSI approaches for co-amoxiclav susceptibility testing conditions for clinical categorization of a collection of Escherichia coli isolates with characterized resistance phenotypes;Diez-Aguilar;J Antimicrob Chemother,2015

3. Consequences of switching from a fixed 2:1 ratio of amoxicillin/clavulanate (CLSI) to a fixed concentration of clavulanate (EUCAST) for susceptibility testing of Escherichia coli;Leverstein-van Hall;J Antimicrob Chemother,2013

4. MIC of amoxicillin/clavulanate according to CLSI and EUCAST: discrepancies and clinical impact in patients with bloodstream infections due to Enterobacteriaceae;Delgado-Valverde;J Antimicrob Chemother,2017

5. English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR). Report 2019 to 2020;UKHSA

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