CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level-Reference-Cited by-同舟云学术

CRISPR/Cas9-mediated gene knockout is insensitive to target copy number but is dependent on guide RNA potency and Cas9/sgRNA threshold expression level

Published:2017-09-25 Issue:20 Volume:45 Page:12039-12053
ISSN:0305-1048
Container-title:Nucleic Acids Research
language:en
Short-container-title:

Author:

Yuen Garmen,Khan Fehad J.,Gao Shaojian,Stommel Jayne M.,Batchelor Eric,Wu Xiaolin,Luo Ji

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

http://academic.oup.com/nar/article-pdf/45/20/12039/21743310/gkx843.pdf

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5. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity;Science,2012

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