Laboratory capacity expansion: lessons from establishing molecular testing in regional referral laboratories in Ethiopia

Author:

Chekol Leulseged1,Waktola Ebba1,Nawaz Saira23,Tadesse Lehageru1,Muluye Samuel1,Bonger Zelalem1,Bogale Addisu1,Eshetu Frehywot4,Degefaw Desalegne1,Tayachew Adamu5,Delelegn Hulemenaw4,Daves Sharon4,Seyoum Eyasu1,Moon Kyle2,Melese Daniel5,Balada Joan-Miquel6,Wang Shu-Hua67,Williams Desmond2,Gebreyes Wondwossen78,Mekuria Zelalem78

Affiliation:

1. Global One Health Initiative - East Africa Regional Office, Office of International Affairs, Ohio State University , Bole Road, Noah Plaza Building, Addis Ababa , Ethiopia

2. Center for Health Outcomes and Policy Evaluation Studies, Ohio State University College of Public Health , 381 Cunz Hall, 1841 Neil Avenue, Columbus, Ohio , USA

3. Division of Health Services Management and Policy, Ohio State University College of Public Health , 250 Cunz Hall, 1841 Neil Avenue, Columbus, Ohio , USA

4. Division of Global Health Protection, US Centers for Disease Control & Prevention , Addis Ababa , Ethiopia

5. Ethiopian Public Health Institute , Addis Ababa , Ethiopia

6. Division of Infectious Diseases, Department of Internal Medicine, The Ohio State University , Columbus, Ohio , USA

7. Global One Health initiative (GOHi), Office of International Affairs, The Ohio State University , Columbus, Ohio , USA

8. Department of Veterinary Preventive Medicine, Ohio State University College of Veterinary Medicine , 1920 Coffey Road, Columbus, Ohio , USA

Abstract

Abstract Respiratory viruses contribute to high morbidity and mortality in Africa. In 2020, the Ohio State University's Global One Health Initiative, in collaboration with the Ethiopian Public Health Institute and the US Centers for Disease Control and Prevention, took action to strengthen Ethiopia's existing respiratory virus surveillance system through decentralization of laboratory testing and scale-up of national and regional capacity for detecting respiratory viruses. In August 2022, four regional laboratories were established, thereby raising the number of reference laboratories conducting respiratory virus surveillance to five. This article highlights lessons learned during implementation and outlines processes undertaken for laboratory scale-up and decentralization.

Funder

Centers for Disease Control and Prevention

Publisher

Oxford University Press (OUP)

Reference5 articles.

1. A review of the surveillance systems of influenza in select;Sanicas;Pan Afr Med J,2014

2. Challenges of establishing routine influenza sentinel surveillance in Ethiopia, 2008–2010;Ayele;J Infect Dis,2012

3. Laboratory capacity building for the International Health Regulations (IHR [2005]) in resource-poor countries: The experience of the African Field Epidemiology Network (AFENET);Masanza;BMC Public Health,2010

4. The SLMTA programme: Transforming the laboratory landscape in developing countries;Yao;Afr J Lab Med,2016

5. Combatting global infectious diseases: A network effect of specimen referral systems;Fonjungo;Clin Infect Dis,2017

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