Prevalence and determinants of cardiovascular risk factors in Lesotho: a population-based survey

Author:

González Fernández Lucia1234,Firima Emmanuel123,Gupta Ravi5,Sematle Mamoronts'ane Pauline5,Khomolishoele Makhebe5,Molulela Manthabiseng5,Bane Matumaole5,Meli Raphaela4,Tlahali Mosa6,Lee Tristan123,Chammartin Frédérique13,Gerber Felix123,Lejone Thabo Ishmael13,Ayakaka Irene5,Weisser Maja237,Amstutz Alain13,Labhardt Niklaus Daniel13ORCID

Affiliation:

1. Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel , Basel , Switzerland

2. Department of Medicine, Swiss Tropical and Public Health Institute , Allschwil, Basel, 4051 , Switzerland

3. University of Basel , Basel , Switzerland

4. SolidarMed, Partnerships for Health , Luzern , Switzerland

5. SolidarMed, Partnerships for Health , Maseru , Lesotho

6. Mokhotlong District Health Management Team, Mokhotlong, Ministry of Health Lesotho

7. Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel , Basel , Switzerland

Abstract

Abstract Background There are no recent data on the prevalence of cardiovascular risk factors (CVDRFs) in Lesotho. This study aims to assess the prevalence of CVDRFs and their determinants. Methods We conducted a household-based, cross-sectional survey among adults ≥18 y of age in 120 randomly sampled clusters in two districts. Results Among 6061 participants, 52.2% were female and their median age was 39 y (interquartile range 27–58). The overall prevalence of overweight, diabetes, elevated blood pressure (BP) and tobacco use was 39.9%, 5.3%, 21.6% and 24.9%, respectively. Among participants, 34.6% had none, 45.2% had one and 20.2% had two or more CVDRFs. Women were more likely to have two or more CVDRFs (20.7% vs 12.3%). Overall, 7.5% of participants had elevated total cholesterol, 52.7% had low high-density lipoprotein cholesterol and 1.6% had elevated low-density lipoprotein cholesterol. Among younger participants (18–29 y), 16.1% reported tobacco use, 28.6% were overweight, 1.5% had diabetes and 3.5% had elevated BP. Household wealth positively correlated with the prevalence of elevated BP, overweight and diabetes, whereas tobacco use was higher among people in the lowest three wealth quintiles. Conclusions CVDRFs are highly prevalent in Lesotho across age and sex groups, underlining the importance of strengthening prevention and care programs in Lesotho and similar settings in southern Africa.

Funder

Swiss Agency for Development and Cooperation

Swiss National Science Foundation

European Union

Publisher

Oxford University Press (OUP)

Subject

Public Health, Environmental and Occupational Health,General Medicine,Health (social science)

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