Dietary glycine prevents the development of liver tumors caused by the peroxisome proliferator WY-14,643

Author:

Rose Michelle L.,Cattley Russell C.,Dunn Corrie,Wong Victoria,Li Xiang,Thurman Ronald G.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference34 articles.

1. Reddy,J.K. and Lalwani,N.D. ( 1983 ) Carcinogenesis by hepatic peroxisome proliferators: Evaluation of the risk of hypolipidemic drugs and industrial plasticizers to humans. CRC Crit. Rev. Toxicol. , 12 , 1 –58.

2. Reddy,J.K., Azarnoff,D.L. and Hignite,C.E. ( 1980 ) Hypolidaemic hepatic peroxisome proliferators form a novel class of chemical carcinogens. Nature (London) , 283 , 397 –398.

3. Marsman,D.S., Cattley,R.C., Conway,J.G. and Popp,J.A. ( 1988 ) Relationship of hepatic peroxisome proliferation and replicative DNA synthesis to the hepatocarcinogenicity of the peroxisome proliferators di(2-ethylhexyl)phthalate and (4-chloro-6-(2,3-xylidino)-2-pyrimidinyl-thio) acetic acid (Wy-14,643) in rats. Cancer Res. , 48 , 6739 –6744.

4. Cattley,R.C., Marsmann,D.S. and Popp,J.A. ( 1991 ) Age-related susceptibility to the carcinogenic effect of the peroxisome proliferator WY-14,643 in rat liver. Carcinogenesis , 12 , 469 –473.

5. Grasl-Kraupp,B., Huber,W., Taper,H. and Schulte-Hermann,R. ( 1991 ) Increased susceptibility of aged rats to hepatocarcinogenesis by the peroxisome proliferator nafenopin and the possible involvement of altered liver foci occurring spontaneously. Cancer Res. , 51 , 666 –671.

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