Comparison of the DNA adducts formed by tamoxifen and 4-hydroxytamoxifen in vivo

Author:

Beland Frederick A.,McDaniel L. Patrice,Marques M. Matilde

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference68 articles.

1. Early Breast Cancer Trialists' Collaborative Group (1998) Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet, 351, 1451–1467.

2. Ault,A. and Bradbury,J. (1998) Experts argue about tamoxifen prevention trial. Lancet, 351, 1107.

3. Greaves,P., Goonetilleke,R., Nunn,G., Topham,J. and Orton,T. (1993) Two-year carcinogenicity study of tamoxifen in Alderley Park Wistar-derived rats. Cancer Res., 53, 3919–3924.

4. Hard,G.C., Iatropoulos,M.J., Jordan,K., Radi,L., Kaltenberg,O.P., Imondi,A.R. and Williams,G.M. (1993) Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female CrI:CD (BR) rats. Cancer Res., 53, 4534–4541.

5. Williams,G.M., Iatropoulos,M.J., Djordjevic,M.V. and Kaltenberg,O.P. (1993) The triphenylethylene drug tamoxifen is a strong liver carcinogen in the rat. Carcinogenesis, 14, 315–317.

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