Potency of dietary indole-3-carbinol as a promoter of aflatoxin B1-initiated hepatocarcinogenesis: results from a 9000 animal tumor study

Author:

Oganesian Aram,Hendricks Jerry D.,Pereira Cliff B.,Orner Gayle A.,Baileyand George S.,Williams David E.

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,General Medicine

Reference65 articles.

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2. Preobrazhenskaya,M.N., Bukhman,V.M., Korolev,A.M. and Efimov,S.A. (1993) Ascorbigen and other indole-derived compounds from Brassica vegetables and their analogs as anticarcinogenic and immunomodulating agents. Pharmacol. Ther., 60, 301–313.

3. Dashwood,R.H., Fong,A.T., Hendricks,J.D. and Bailey,G.S. (1990) Tumor dose–response studies with aflatoxin B1 and the ambivalent modulator indole-3-carbinol: inhibitory versus promotional potency. In Kuroda,Y., Shankei,D.M. and Waters,M.D. (eds) Antimutagenesis and Anticarcinogenesis Mechanisms. Plenum Publishing, New York, NY, pp. 361–365.Dashwood,R.H., Fong,A.T., Hendricks,J.D. and Bailey,G.S. (1990) Tumor dose–response studies with aflatoxin B1 and the ambivalent modulator indole-3-carbinol: inhibitory versus promotional potency. In Kuroda,Y., Shankei,D.M. and Waters,M.D. (eds) Antimutagenesis and Anticarcinogenesis Mechanisms. Plenum Publishing, New York, NY, pp. 361–365.

4. Tanaka,T., Mory,Y., Morishita,Y., Hara,A., Ohno,T., Kojima,T. and Mori,H. (1990) Inhibitory effect of sinigrin and indole-3-carbinol on diethylnitrosamine-induced hepatocarcinogenesis in male ACI/N rats. Carcinogenesis, 11, 1403–1406.

5. Grubbs,C.J., Steele,V.E., Casebolt,T., Juliana,M.M., Eto,I., Whitaker,L.M., Dragnev,K.H., Kelloff,G.J. and Lubet,R.L. (1995) Chemoprevention of chemically-induced mammary carcinogenesis by indole-3-carbinol. Anticancer Res., 15, 709–716.

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