Buena VISTA: a promising outlook on targeting immune checkpoint regulators to combat sepsis-Reference-Cited by-同舟云学术

Buena VISTA: a promising outlook on targeting immune checkpoint regulators to combat sepsis

Published:2024-03-25 Issue:6 Volume:115 Page:1002-1004
ISSN:1938-3673
Container-title:Journal of Leukocyte Biology
language:en
Short-container-title:

Author:

Mott Madeline D¹,Trusiano Briana²,Allen Irving Coy¹²³^ORCID

Affiliation:

1. Graduate Program in Translational Biology, Medicine, and Health, Virginia Polytechnic Institute and State University , 1 Riverside Circle Suite 201, Roanoke, VA 24016 , United States

2. Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine , 205 Duck Pond Dr, Blacksburg, VA 24061 , United States

3. Department of Basic Science Education, Virginia Tech Carilion School of Medicine , 2 Riverside Circle, Roanoke, VA 24016 , United States

Abstract

Regulation of T cell activation by VISTA is implicated in host organism immune response to sepsis and may be a potential therapeutic target.

Publisher

Oxford University Press (OUP)

Link

https://academic.oup.com/jleukbio/advance-article-pdf/doi/10.1093/jleuko/qiae080/57390573/qiae080.pdf

Reference10 articles.

1. Pathophysiology of sepsis;Remick;Am J Pathol,2007

2. VISTA Re-programs macrophage biology through the combined regulation of tolerance and anti-inflammatory pathways;ElTanbouly;Front Immunol,2020

3. Vista non-redundantly regulates proliferation and cd69low γδ T cell accumulation in the intestine in murine sepsis;Gray;J Leukoc Biol,2024

4. High-affinity anti-VISTA antibody protects against sepsis by inhibition of T lymphocyte apoptosis and suppression of the inflammatory response;Tao;Mediators Inflamm,2021

5. VISTA stimulation of VSIG4-positive macrophages strongly suppresses T cell proliferation via excessive nitric oxide production in sepsis;Lee;Biol Pharm Bull,2021