Of mice, or men: TLR4 signaling in HIV pathogenesis-Reference-Cited by-同舟云学术

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Of mice, or men: TLR4 signaling in HIV pathogenesis

Published:2023-02-15 Issue:5 Volume:113 Page:415-417
ISSN:1938-3673
Container-title:Journal of Leukocyte Biology
language:en
Short-container-title:

Author:

Acosta Reyes¹²,Claiborne Daniel T²^ORCID

Affiliation:

1. Department of Microbiology, Perelman School of Medicine, University of Pennsylvania , 3451 Walnut Street, Philadelphia, PA 19104 , United States

2. Vaccine and Immunotherapy Center, The Wistar Institute , 3601 Spruce Street, Philadelphia, PA 19104 , United States

Abstract

A murine Tlr4null humanized mouse model offers a new tool to study mechanisms by which microbial translocation affects adaptive immune function and exacerbates HIV-1 pathogenesis.

Publisher

Oxford University Press (OUP)

Subject

Cell Biology,Immunology,Immunology and Allergy

Link

https://academic.oup.com/jleukbio/advance-article-pdf/doi/10.1093/jleuko/qiad017/49504400/qiad017.pdf

Reference11 articles.

1. Microbial translocation, immune activation, and HIV disease;Klatt;Trends Microbiol,2013

2. Microbial translocation in HIV infection: causes, consequences and treatment opportunities;Sandler;Nat Rev Microbiol,2012

3. A review of potential microbiome-gut-brain axis mediated neurocognitive conditions in persons living with HIV;Rich;Brain Behav Immun Health,2020

4. Toll-like receptors and the control of immunity;Fitzgerald;Cell,2020

5. Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis;Claiborne;PLoS Pathog,2019

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