Affiliation:
1. Arboviral Diseases Branch, Division of Vector-Borne Infectious Diseases, U.S. Centers for Disease Control and Prevention , 3156 Rampart Road, Fort Collins, CO 80521 , USA
Abstract
Abstract
Cache Valley virus (CVV) is a mosquito-borne virus in the genus Orthobunyavirus (Bunyavirales: Peribunyaviridae) that has been identified as a teratogen in ruminants causing fetal death and severe malformations during epizootics in the U.S. CVV has recently emerged as a viral pathogen causing severe disease in humans. Despite its emergence as a public health and agricultural concern, CVV has yet to be significantly studied by the scientific community. Limited information exists on CVV’s geographic distribution, ecological cycle, seroprevalence in humans and animals, and spectrum of disease, including its potential as a human teratogen. Here, we present what is known of CVV’s virology, ecology, and clinical disease in ruminants and humans. We discuss the current diagnostic techniques available and highlight gaps in our current knowledge and considerations for future research.
Publisher
Oxford University Press (OUP)
Subject
Infectious Diseases,Insect Science,General Veterinary,Parasitology
Cited by
3 articles.
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