1. Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS , Rome 00168 , Italy
2. Division of Cardiology, Department of Medicine, Karolinska Institutet , Stockholm 17176 , Sweden
3. Heart and Vascular and Neurology Theme, Karolinska University Hospital , Stockholm 17176 , Sweden
4. Department of Translational Medicine, Università del Piemonte Orientale , Novara 28100 , Italy
5. Division of Cardiology, AOU Maggiore della Carità , Novara 28100 , Italy