Subgroup analyses in randomized clinical trials: value and limitations. Review #3 on important aspects of randomized clinical trials in cardiovascular pharmacotherapy

Author:

Drexel Heinz1234ORCID,Pocock Stuart J5,Lewis Basil S67,Saely Christoph H138,Kaski Juan Carlos9,Rosano Giuseppe M C10,Tautermann Gerda138,Huber Kurt1112,Dopheide Joern F113,Mader Arthur138,Niessner Alexander14,Savarese Gianluigi15,Schmidt Thomas A16,Semb Anne Grete17,Tamargo Juan18,Wassmann Sven1920,Clodi Martin21,Kjeldsen Keld Per2223,Agewall Stefan2425

Affiliation:

1. Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT), Feldkirch, Austria

2. Department of Medicine, County Hospital Bregenz, Bregenz, Austria

3. Private University of the Principality of Liechtenstein, Triesen, Liechtenstein

4. Drexel University College of Medicine, Philadelphia, USA

5. Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK

6. Cardiovascular Clinical Research Institute, Lady Davis Carmel Medical Center, Haifa, Israel

7. Ruth and Bruce Rappaport School of Medicine, Technion—Israel Institute of Technology, Haifa, Israel

8. Department of Medicine I, Academic Teaching Hospital Feldkirch, Feldkirch, Austria

9. Molecular and Clinical Sciences Research Institute, St George's University of London, London, UK

10. Department of Medical Sciences, IRCCS San Raffaele Hospital, Rome, Italy

11. 3rd Medical Department, Cardiology and Intensive Care Medicine, Wilhelminen Hospital, Vienna, Austria

12. Department of Cardiology, Medical School, Sigmund Freud University, Vienna, Austria

13. Department of Angiology, Cantonal Hospital of Graubünden, Chur, Switzerland

14. Department of Internal Medicine II, Medical University of Vienna, Vienna, Austria

15. Cardiology Unit, Department of Medicine, Karolinska University Hospital, Stockholm, Sweden

16. Department of Emergency Medicine, North Zealand University Hospital, Hillerød, Denmark

17. Preventive Cardio-Rheuma Clinic, Division of Rheumatology and Research, Diakonhjemmet Hospital, Oslo, Norway

18. Department of Pharmacology and Toxicology, School of Medicine, Universidad Complutense, CIBERCV, Madrid, Spain

19. Cardiology Pasing, Munich, Germany

20. Medical Faculty, Clinical Medicine, University of the Saarland, Homburg/Saar, Germany

21. Department of Medicine, St John of God Hospital Linz, Linz, Austria

22. Department of Cardiology, Copenhagen University Hospital (Amager-Hvidovre), Copenhagen, Denmark

23. Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark

24. Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway

25. Institute of Clinical Sciences, Søsterhjemmet, University of Oslo, Oslo, Norway

Publisher

Oxford University Press (OUP)

Subject

Pharmacology (medical),Cardiology and Cardiovascular Medicine

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