A Delphi Consensus report from the "Prolonged Air Leak: A Survey" study group on prevention and management of postoperative air leaks after minimally invasive anatomical resections

Author:

Zaraca Francesco1ORCID,Brunelli Alessandro2ORCID,Pipitone Marco Damiano1ORCID,Abdellateef Amr3ORCID,Abu Akar Firas4ORCID,Augustin Florian5ORCID,Batchelor Tim6,Bertani Alessandro7ORCID,Crisci Roberto8ORCID,D’Amico Thomas9,D'Journo Xavier Benoit10ORCID,Droghetti Andrea11ORCID,Fang Wentao12ORCID,Gonfiotti Alessandro13ORCID,Janík Miroslav14ORCID,Jiménez Marcelo15ORCID,Kirschbaum Andreas16ORCID,Kostic Marko17ORCID,Lazzaro Richard18ORCID,Lucchi Marco19ORCID,Marra Alessandro20ORCID,Murthy Sudish21ORCID,Ng Calvin S H22ORCID,Nachira Dania23ORCID,Pardolesi Alessandro24ORCID,Perkmann Reinhold1,Petersen René Horsleben25ORCID,Pischik Vadim26ORCID,Russo Michele Dario1ORCID,Opitz Isabelle27ORCID,Spaggiari Lorenzo2829ORCID,Ugalde Paula A30ORCID,Vannucci Fernando3132ORCID,Veronesi Giulia33ORCID,Bertolaccini Luca28ORCID

Affiliation:

1. Department of Vascular and Thoracic Surgery, Regional Hospital , Bozen/Bolzano, Italy

2. Department of Thoracic Surgery, St. James’s University Hospital , Leeds, UK

3. Department of Cardiothoracic Surgery, Mansoura University Hospital , Mansoura, Egypt

4. Department of Cardiothoracic Surgery, Al-Makassed Charitable Society Hospital , East Jerusalem, Palestine

5. Department of Visceral, Transplant, and Thoracic Surgery, Medical University of Innsbruck , Innsbruck, Austria

6. Department of Thoracic Surgery, Bristol Royal Infirmary , Bristol, UK

7. Division of Thoracic Surgery and Lung Transplantation, Department for the Treatment and Study of Cardiothoracic Diseases and Cardiothoracic Transplantation, IRCCS ISMETT—UPMC , Palermo, Italy

8. Division of Thoracic Surgery, Thoracic Surgery Unit, University of L’Aquila, G. Mazzini Hospital , Teramo, Italy

9. Department of Surgery, Duke Cancer Institute , Durham, North Carolina, USA

10. Department of Thoracic Surgery, Aix-Marseille Université, APHM, Hôpital Nord , Marseille, France

11. Division of Thoracic Surgery, ASST Mantova , Mantova, Italy

12. Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University , Shanghai, China

13. Thoracic Surgery Unit, Careggi University Hospital , Florence, Italy

14. Department of Thoracic Surgery, Slovak Medical University, University Hospital Bratislava , Bratislava, Slovakia

15. Department of Thoracic Surgery, Salamanca University Hospital , Salamanca, Spain

16. Department of Visceral, Thoracic and Vascular Surgery, University of Marburg , Marburg, Germany

17. Clinic for Thoracic Surgery, University Clinical Center of Serbia, University of Belgrade , Belgrade, Serbia

18. Department of Cardiothoracic Surgery, Lenox Hill Hospital , New York, USA

19. Division of Thoracic Surgery, Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa , Pisa, Italy

20. Department of Thoracic Surgery, Rems-Murr-Klinikum Winnenden , Winnenden, Germany

21. Department of Thoracic and Cardiovascular Surgery, Heart, Vascular and Thoracic Institute, Cleveland Clinic , Cleveland, Ohio, USA

22. The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin , New Territories, Hong Kong, China

23. Department of General Thoracic Surgery, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore , Rome, Italy

24. Division of Thoracic Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori , Milan, Italy

25. Department of Cardiothoracic Surgery, Copenhagen University Hospital , Rigshospitalet, Copenhagen, Denmark

26. Department of Thoracic Surgery, St Petersburg City Oncology Center, St Petersburg State University , Saint Petersburg, Russia

27. Department of Thoracic Surgery, University Hospital Zurich , Zurich, Switzerland

28. Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS , Milan, Italy

29. Department of Oncology and Hemato-Oncology, University of Milan , Milan, Italy

30. Department of Thoracic Surgery, Institut Universitaire de Pneumologie et Cardiologie de Quebec , Quebec, Quebec, Canada

31. Thoracic Surgery Unit, Hospital Pró-Cardíaco—Botafogo , Rio de Janeiro, Brazil

32. Thoracic Surgery Unit, Hospital Central da Polícia Militar , Rio de Janeiro, Brazil

33. Department of Thoracic Surgery, Vita-Salute San Raffaele University , Milan, Italy

Abstract

Abstract OBJECTIVES This study reports the results of an international expert consensus process evaluating the assessment of intraoperative air leaks (IAL) and treatment of postoperative prolonged air leaks (PAL) utilizing a Delphi process, with the aim of helping standardization and improving practice. METHODS A panel of 45 questions was developed and submitted to an international working group of experts in minimally invasive lung cancer surgery. Modified Delphi methodology was used to review responses, including 3 rounds of voting. The consensus was defined a priori as >50% agreement among the experts. Clinical practice standards were graded as recommended or highly recommended if 50–74% or >75% of the experts reached an agreement, respectively. RESULTS A total of 32 experts from 18 countries completed the questionnaires in all 3 rounds. Respondents agreed that PAL are defined as >5 days and that current risk models are rarely used. The consensus was reached in 33/45 issues (73.3%). IAL were classified as mild (<100 ml/min; 81%), moderate (100–400 ml/min; 71%) and severe (>400 ml/min; 74%). If mild IAL are detected, 68% do not treat; if moderate, consensus was not; if severe, 90% favoured treatment. CONCLUSIONS This expert consensus working group reached an agreement on the majority of issues regarding the detection and management of IAL and PAL. In the absence of prospective, randomized evidence supporting most of these clinical decisions, this document may serve as a guideline to reduce practice variation.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,General Medicine,Surgery

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