Saphenous vein to the right coronary system from the right thoracic artery or the aorta. Long-term propensity-matched results of 2 groups

Author:

Prapas Sotirios1ORCID,Katsavrias Konstantinos1,Gaudino Mario2ORCID,Puskas John D3,Di Mauro Michele45ORCID,Zografos Panayiotis1,Guarracini Stefano5,Linardakis Ioannis1,Panagiotopoulos Ioannis6,Di Marco Massimo7,Papandreopoulos Styliani1,Pomakidou Sofia8,Totaro Antonio9,Calafiore Antonio M1ORCID

Affiliation:

1. 1st Department of Cardiac Surgery A, Henry Dunant Hospital , Athens, Greece

2. Department of Cardiothoracic Surgery, Weill Cornell Medicine , New York, NY, USA

3. Department of Cardiovascular Surgery, Mount Sinai Hospital and Icahn School of Medicine at Mount Sinai , New York, NY, USA

4. Cardio-Thoracic Surgery Unit, Heart and Vascular Centre, Maastricht University Medical Centre (MUMC), Cardiovascular Research Institute Maastricht (CARIM) , Maastricht, Netherlands

5. Department of Cardiology, “Pierangeli” Hospital , Pescara, Italy

6. Division of Cardiac Surgery, Hippokratio General Hospital , Athens, Greece

7. Department of Cardiology, “S Spirito” Hospital , Pescara, Italy

8. EVO Human Performance

9. Department of Medicine and Health Sciences, University of Molise , Campobasso, Italy

Abstract

Abstract OBJECTIVES Since 2000, we anastomosed the saphenous vein graft to the right coronary artery system using the stump of the right internal thoracic artery as inflow. The long-term results of patients where the right coronary artery was grafted with the right internal thoracic artery or the ascending aorta as saphenous vein inflow has not been reported. METHODS From 2000 to 2018, 699 consecutive patients had right internal thoracic artery elongated with saphenous vein (I-graft group, n = 358, 51.2%) or saphenous vein from the aorta (Ao-graft group, n = 341, 48.8%) on right coronary artery system. Inclusion criteria were age ≤75 years, bilateral internal thoracic arteries as a Y graft on the left system (three-vessel disease, n = 603, 86.3%) or as a left internal thoracic artery on left anterior descending and right internal thoracic artery elongated with saphenous vein on the right coronary artery system (two-vessel disease, n = 96, 13.7%), only 1 saphenous vein per patient. Propensity-matching identified 272 patients per group. One-hundred and twenty-two patients underwent coronary computed tomographic angiography to asses grafts patency after a median follow-up of 88 (65–93) months. RESULTS In the paired samples, there was no difference in the early outcome. Ten-year survival and freedom from death, non-fatal acute myocardial infarction and repeat revascularization were higher in I-graft group: 90.6 [standard error (SE): 2.0] vs 78.2 (SE: 5.3), P = 0.0266, and 85.2 (SE: 2.4) vs 69.9 (SE: 5.3), P = 0.0179. Saphenous vein graft, at a long-time follow-up, showed a higher patency rate (81.6% (SE: 7.0) vs 50.7% (SE: 7.9), P < 0.0001) and a smaller internal lumen diameter (2.7, standard deviation: 0.4 vs 3.4, standard deviation: 0.6 mm, P < 0.0001) when right internal thoracic artery was the inflow. CONCLUSIONS Grafting the right coronary artery with saphenous vein may entail higher patency rate and better outcome when the inflow is the right internal thoracic artery than when is the ascending aorta. Prospective randomized data are needed to test this hypothesis.

Publisher

Oxford University Press (OUP)

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