Impact of T-cell-mediated immune response on xenogeneic heart valve transplantation: short-term success and mid-term failure

Author:

Biermann Anna C123,Marzi Julia34,Brauchle Eva34,Schneider Maria56,Kornberger Angela7,Abdelaziz Sherif1,Wichmann Julian L8,Arendt Christophe T8,Nagel Eike8,Brockbank Kelvin G M910,Seifert Martina56,Schenke-Layland Katja3411,Stock Ulrich A121213

Affiliation:

1. Department of Thoracic and Cardiovascular Surgery, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany

2. Department of Cardiothoracic Surgery, Royal Brompton and Harefield Foundation Trust, Harefield, UK

3. Department of Women’s Health, Research Institute for Women's Health, Eberhard-Karls-University, Tuebingen, Germany

4. Department of Cell and Tissue Engineering, Fraunhofer Institute for Interfacial Engineering and Biotechnology (IGB), Stuttgart, Germany

5. Institue of Medical Immunology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany

6. Berlin-Brandenburg Center of Regenerative Therapies (BCRT), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany

7. Department of Cardiothoracic and Vascular Surgery, Johannes Gutenberg-University, Mainz, Germany

8. Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany

9. Tissue Testing Technologies LLC, North Charleston, SC, USA

10. Department of Bioengineering, Clemson University, North Charleston, SC, USA

11. Department of Medicine / Cardiology, Cardiovascular Research Laboratories, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA

12. Faculty of Medicine, Imperial College London, London, UK

13. Magdi Yacoub Institute, Heart Science Centre, Harefield, UK

Funder

German Research Foundation

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,General Medicine,Surgery

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