Is perioperative fast-track management the future of proximal aortic repair?

Author:

Haunschild Josephina1ORCID,van Kampen Antonia12,Misfeld Martin13456,Von Aspern Konstantin7ORCID,Ender Jörg8,Zakhary Waseem8,Borger Michael A1,Etz Christian D1ORCID

Affiliation:

1. University Department for Cardiac Surgery, Leipzig Heart Center , Leipzig, Germany

2. Division of Cardiac Surgery, Massachusetts General Hospital, Harvard Medical School , Boston, MA, United States

3. Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital , Sydney, NSW, Australia

4. Sydney Medical School, University of Sydney , Sydney, NSW, Australia

5. Institute of Academic Surgery, RPAH , Sydney, NSW, Australia

6. The Baird Institute of Applied Heart and Lung Surgical Research , Sydney, NSW, Australia

7. Department for Cardiothoracic Surgery, Klinikum Links der Weser , Bremen, Germany

8. Department of Anaesthesiology and Intensive care Medicine, Leipzig Heart Center , Leipzig, Germany

Abstract

Abstract OBJECTIVES The Bentall procedure is the gold standard for patients with combined aortic root dilation and valve dysfunction. Over the past decade, fast-track (FT) perioperative anaesthetic management protocols have progressively evolved. We reviewed our results for selected patients undergoing Bentall surgery under an FT protocol. METHODS We retrospectively analysed a consecutive cohort of patients who underwent elective Bentall procedures at our institution between 2000 and 2018. Complex aortic root repair (i.e. David and Ross procedure, redo surgery, major concomitant procedures, emergency repair for acute dissections) was excluded. Patients who underwent conventional perioperative treatment and those treated according to our institutional FT concept were compared following 1:1 propensity score matching. RESULTS Of 772 patients who fit the in- and exclusion criteria, 565 were treated conventionally post-surgery, while 207 were treated using the FT protocol. Propensity score matching resulted in 197 pairs, with no differences in baseline characteristics after matching. In-house mortality, 30-day mortality and overall all-cause long-term mortality were comparable between the FT and the conventionally treated cohort. Postoperative anaesthetic care unit/intensive care unit length-of-stay (6.2 vs 20.6 h, P = 0.03) and postoperative ventilation times (158.9 vs 465.5 min, P < 0.001) were significantly shorter in the FT cohort. There were no differences in rates of postoperative adverse events. CONCLUSIONS In centres with experienced anaesthesiologists, perioperative FT management is non-inferior to conventionally treated patients undergoing elective Bentall procedures without compromising patient safety.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,General Medicine,Surgery

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