Gap distribution mapping to visualize regions associated with type 1 endoleak in a fenestrated thoracic stent graft

Author:

Shukuzawa Kota12ORCID,Fujii Tomoya3,Sumi Makoto4,Kozaki Junya3,Umezu Mitsuo135,Ohki Takao2,Iwasaki Kiyotaka135ORCID

Affiliation:

1. Cooperative Major in Advanced Biomedical Sciences, Joint Graduate School of Tokyo Women’s Medical University and Waseda University , Tokyo, Japan

2. Division of Vascular Surgery, Department of Surgery, The Jikei University School of Medicine , Tokyo, Japan

3. Department of Integrative Bioscience and Biomedical Engineering, Graduate School of Advanced Science and Engineering, Waseda University , Tokyo, Japan

4. Department of Vascular Surgery, Saitama Cardiovascular and Respiratory Center , Saitama, Japan

5. Department of Modern Mechanical Engineering, School of Creative Science and Engineering, Waseda University , Tokyo, Japan

Abstract

Abstract OBJECTIVES Our goal was to analyse the relationships between aortic surface irregularity and a type 1 endoleak (T1EL) after a thoracic endovascular repair using the Najuta fenestrated stent graft. METHODS The patients who were treated using the Najuta stent graft for an intact aortic arch aneurysm at the Saitama Cardiovascular and Respiratory Center between June 2013 and June 2017 were analysed retrospectively. The primary end point was the occurrence of a T1EL. The gap between a virtual aorta and the patient's aortic wall at the stent graft fixation was calculated over the whole circumference at 1 mm intervals, and gap distribution mapping was performed. The rate of freedom from a T1EL was estimated using the Kaplan–Meier method and compared between the patients with or without a continuously malapposed region of >1 mm from the branches to the aneurysm. RESULTS Twenty-one patients were analysed. During the mean follow-up period of 21.7 months, 4 patients were confirmed to have T1ELs. Three of the T1Els were detected during the perioperative period and occurred through a fenestration. The remaining patient had a T1EL 2 years postoperatively. The gap distribution mapping confirmed the presence of a continuously malapposed region of >1 mm from the cervical branch to the aneurysm postoperatively in 4 patients with T1ELs. Patients who had a continuously malapposed region of >1 mm showed a statistically lower T1EL rate than those without (p < 0.001). Malapposed regions defined using the gap distribution mapping were consistent with flow channels through T1EL fenestrations detected using the perioperative computed tomography data. CONCLUSIONS The gap distribution mapping could be useful to predict the occurrence of T1ELs in patients with the Najuta stent graft.

Funder

Japan Agency for Medical Research and Development

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,General Medicine,Surgery

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. 大血管分野2022年の進歩;Japanese Journal of Cardiovascular Surgery;2023-05-15

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