Combined clopidogrel and aspirin treatment up to surgery increases the risk of postoperative myocardial infarction, blood loss and reoperation for bleeding in patients undergoing coronary artery bypass grafting†

Author:

Miceli Antonio1,Duggan Simon M.J.1,Aresu Giuseppe1,de Siena Paolo M.1,Romeo Francesco1,Glauber Mattia1,Caputo Massimo1,Angelini Gianni D.1

Affiliation:

1. Bristol Heart Institute, University of Bristol, Bristol, UK

Funder

NIHR

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Pulmonary and Respiratory Medicine,General Medicine,Surgery

Reference25 articles.

1. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update): a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines;Kushner;J Am Coll Cardiol,2009

2. Clopidogrel increases blood transfusion and hemorrhagic complications in patients undergoing cardiac surgery;Herman;Ann Thorac Surg,2010

3. Impact of clopidogrel in patients with acute coronary syndromes requiring coronary artery bypass surgery;Berger;J Am Coll Cardiol,2008

4. Postoperative blood loss in patients undergoing coronary artery bypass surgery after preoperative treatment with clopidogrel. A prospective randomised controlled study;Firanescu;. Eur J Cardiothorac Surg,2009

5. Impact of clopidogrel in coronary artery bypass grafting;Englberger;Eur J Cardiothorac Surg,2004

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