Likelihood Ratios as Value Proposition for Diagnostic Laboratory Tests

Author:

Fierz Walter1,Bossuyt Xavier23

Affiliation:

1. Schweizerischer Verband der Diagnostikindustrie (SVDI-ASID), Bern, Switzerland

2. Department of Laboratory Medicine, Katholieke Universiteit Leuven, University Hospitals Leuven, Leuven, Belgium

3. Clinical and Diagnostic Immunology, Department of Microbiology, Immunology and Transplantation, Katholieke Universiteit Leuven, University Hospitals Leuven, Leuven, Belgium

Abstract

AbstractThe clinical and health economic value of clinical laboratory diagnostics has been debated increasingly in recent years without resulting in practical recommendations for measuring the effectiveness of diagnostic tests. One way to achieve such a goal could be to enrich the mere data of laboratory test results with additional information about their likelihood ratios for diagnosis. The diagnostic significance of test results can be judged subjectively based on the experience of the treating physician or expressed objectively in the form of likelihood ratios. The provision of likelihood ratios by the laboratory would increase the impact of laboratory diagnostics in healthcare and thus have positive economic value. Consequently, likelihood ratios should be taken into account in reimbursement strategies.

Publisher

Oxford University Press (OUP)

Subject

General Medicine

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