Physical activity and preventable premature deaths from non-communicable diseases in Brazil

Author:

Rezende Leandro Fórnias Machado de1ORCID,Garcia Leandro Martin Totaro2,Mielke Grégore Iven34,Lee Dong Hoon5,Giovannucci Edward567,Eluf-Neto José1

Affiliation:

1. Departamento de Medicina Preventiva, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil

2. UKCRC Centre for Diet and Activity Research, MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge, UK

3. School of Human Movement and Nutrition Sciences, University of Queensland, Brisbane, Australia

4. Postgraduate Program in Epidemiology, Federal University of Pelotas, Brazil

5. Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA

6. Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA

7. Channing Division of Network Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, USA

Abstract

ABSTRACT Background Studies on the impact of counterfactual scenarios of physical activity on premature deaths from non-communicable diseases (NCDs) are sparse in the literature. We estimated preventable premature deaths from NCDs (diabetes, ischemic heart disease, stroke, and breast and colon cancers) in Brazil by increasing population-wide physical activity (i) to theoretical minimum risk exposure levels; (ii) reaching the physical activity recommendation; (iii) reducing insufficient physical activity by 10%; and (iv) eliminating the gender differences in physical activity. Methods Preventable fractions were estimated using data from a nationally representative survey, relative risks from a meta-analysis and number of premature deaths (30–69 years) from the Brazilian Mortality Information System. Results Physical activity could potentially avoid up to 16 700 premature deaths from NCDs in Brazil, corresponding to 5.75 and 3.23% of premature deaths from major NCDs and of all-causes, respectively. Other scenarios suggested the following impact on premature deaths: reaching physical activity recommendation (5000 or 1.74% of major NCDs); 10% reduction in insufficient physical activity (500 or 0.17% of major NCDs); eliminating gender differences in physical activity (1000 or 0.33% of major NCDs). Conclusions Physical activity may play an important role to reduce premature deaths from NCD in Brazil.

Funder

Sao Paulo Research Foundation

Centre for Diet and Activity Research

UKCRC Public Health Research Centre of Excellence

British Heart Foundation, Cancer Research UK

Economic and Social Research Council

Medical Research Council

National Institute for Health Research

Publisher

Oxford University Press (OUP)

Subject

Public Health, Environmental and Occupational Health,General Medicine

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