Use of urea containing dialysate to avoid disequilibrium syndrome, enabling intensive dialysis treatment of a diabetic patient with renal failure and severe metformin induced lactic acidosis
Author:
Publisher
Oxford University Press (OUP)
Subject
Transplantation,Nephrology
Link
http://academic.oup.com/ndt/article-pdf/16/6/1303/23371137/161303.pdf
Reference5 articles.
1. Owen MR, Doran E, Halestrap AP. Evidence that metformin exerts its anti‐diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J2000; 348: 607–614
2. Bailey CJ, Turner RC. Metformin. N Engl J Med1996; 334: 574–579
3. Heaney D, Majid A, Junor B. Bicarbonate haemodialysis as a treatment of metformin overdose. Nephrol Dial Transplant1997; 12: 1046–1047
4. Arieff AI. Dialysis disequilibrium syndrome: current concepts on pathogenesis and prevention. Kidney Int1994; 45: 629–635
5. Silver SM, DeSimone JA, Smith DA, Sterns RH. Dialysis disequilibrium syndrome (DDS) in the rat: Role of the ‘reverse urea effect’. Kidney Int1992; 42: 161–166
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