Neutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma

Author:

Farahi Neda1,Paige Ellie2,Balla Jozef1,Prudence Emily1,Ferreira Ricardo C.3,Southwood Mark1,Appleby Sarah L.1,Bakke Per4,Gulsvik Amund4,Litonjua Augusto A.5,Sparrow David6,Silverman Edwin K.5,Cho Michael H.5,Danesh John2789,Paul Dirk S.2,Freitag Daniel F.2,Chilvers Edwin R.1

Affiliation:

1. Division of Respiratory Medicine, Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK

2. Department of Public Health and Primary Care, Strangeways Research Laboratory, University of Cambridge CB1 8RN, Cambridge, UK

3. JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Nuffield Department of Medicine, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK

4. Department of Clinical Science, University of Bergen, Bergen 5021, Norway

5. Brigham and Women’s Hospital and Harvard Medical School, Boston 02115, MA, USA

6. VA Boston Healthcare System and School of Medicine, Boston University, Boston 02132, MA, USA

7. British Heart Foundation Centre of Excellence, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK

8. NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Cambridge, UK

9. Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK

Funder

UK Medical Research Council

British Heart Foundation

GlaxoSmithKline

National Institutes of Health

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

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