Annexin A2 links poor myofiber repair with inflammation and adipogenic replacement of the injured muscle

Author:

Defour Aurelia1,Medikayala Sushma1,Van der Meulen Jack H.1,Hogarth Marshall W.1,Holdreith Nicholas1,Malatras Apostolos2,Duddy William23,Boehler Jessica1,Nagaraju Kanneboyina14,Jaiswal Jyoti K.14

Affiliation:

1. Center for Genetic Medicine Research, Children’s National Health System, Washington, DC 20010, USA

2. Center for Research in Myology 75013, Sorbonne Universités, UPMC University Paris 06, INSERM UMRS975, CNRS FRE3617, GH Pitié Salpêtrière, Paris 13, Paris, France

3. Northern Ireland Centre for Stratified Medicine, Altnagelvin Hospital Campus, Ulster University, Londonderry, Northern Ireland, BT52 1SJ UK

4. Department of Integrative Systems Biology, George Washington University School of Medicine and Health Sciences, Washington, DC, 20052 USA

Funder

National Institute of Arthritis and Musculoskeletal and Skin diseases

National Institute of Health

Muscular Dystrophy Association

Association Française contre les Myopathies, National Institute of Health

Publisher

Oxford University Press (OUP)

Subject

Genetics (clinical),Genetics,Molecular Biology,General Medicine

Reference67 articles.

1. Inflammatory processes in muscle injury and repair. Am;Tidball;J. Physiol Regul. Integr. Comp. Physiol,2005

2. Disruptions of muscle fiber plasma membranes. Role in exercise-induced damage;McNeil;Am. J. Pathol,1992

3. Annexins: linking Ca2+ signalling to membrane dynamics;Gerke;Nat. Rev. Mol. Cell Biol,2005

4. Annexin A6 modifies muscular dystrophy by mediating sarcolemmal repair;Swaggart;Proc. Natl. Acad. Sci. U. S. A,2014

5. Annexin expression in inflammatory myopathies;Probst-Cousin;Muscle Nerve,2004

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