Eight-day Inpatient Directly Observed Therapy for Antiretroviral Therapy (ART) Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support-Reference-Cited by-同舟云学术

Eight-day Inpatient Directly Observed Therapy for Antiretroviral Therapy (ART) Failure: A Tool For Preventing Unnecessary ART Changes and Optimizing Adherence Support

Published:2019-07-11 Issue:6 Volume:70 Page:1222-1225
ISSN:1058-4838
Container-title:Clinical Infectious Diseases
language:en
Short-container-title:

Author:

Winchester Nicole E¹,Maldarelli Frank²,Mejia Yolanda³,Dee Nicola³,Dewar Robin³,Laidlaw Elizabeth¹,Kuriakose Safia S³,Stoll Pamela⁴,Proschan Michael¹,Lane H Clifford¹,Pau Alice K¹

Affiliation:

1. National Institute of Allergy and Infectious Diseases, Bethesda

2. National Cancer Institute, Frederick

3. Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, National Cancer Institute, Bethesda, Maryland

4. Clinical Center, National Institutes of Health, Bethesda, Maryland

Abstract

Abstract Eight-day inpatient directly observed therapy confirmed nonadherence as the major cause of virologic failure for 9 (45%) of 20 highly treatment-experienced persons with human immunodeficiency virus, extensive antiretroviral drug resistance, and high self-reported adherence rates, preventing unnecessary regimen changes.

Funder

Intramural Research Program of the National Institute of Allergy and Infectious Diseases

National Institutes of Health

National Cancer Institute

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

Link

http://academic.oup.com/cid/advance-article-pdf/doi/10.1093/cid/ciz590/29181948/ciz590.pdf

Reference12 articles.

1. HIV viral suppression trends over time among HIV-infected patients receiving care in the United States, 1997 to 2015: a cohort study;Nance;Ann Intern Med,2018